AUTOLOGOUS DENDRITIC CELL THERAPY IN MESOTHELIOMA PATIENTS ENHANCES FREQUENCIES OF PERIPHERAL CD4 T CELLS EXPRESSING HLA-DR, PD-1, OR ICOS

Autologous Dendritic Cell Therapy in Mesothelioma Patients Enhances Frequencies of Peripheral CD4 T Cells Expressing HLA-DR, PD-1, or ICOS

Introduction: Malignant pleural mesothelioma (MPM) is a malignancy with a very poor prognosis for top bar mega which new treatment options are urgently needed.We have previously shown that dendritic cell (DC) immunotherapy provides a clinically feasible treatment option.In the current study, we set out to assess the immunological changes induced by

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The challenges and opportunities of conducting a clinical trial in a low resource setting: The case of the Cameroon mobile phone SMS (CAMPS) trial, an investigator initiated trial

Abstract Conducting clinical trials in developing countries often presents significant ethical, organisational, cultural and infrastructural challenges to researchers, pharmaceutical companies, sponsors and regulatory bodies.Globally, these regions are under-represented in research, yet this population stands to gain more from research in these set

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The public washroom - friend or foe? An observational study of washroom cleanliness combined with microbiological investigation of hand hygiene facilities

Abstract Background Many people use handwashing and hand-drying facilities in public washrooms under the impression that these amenities are hygienic.However, such facilities may be potential sites for the transmission of pathogenic bacteria.This study aimed to nucleus ball toy examine the hygiene facilities provided including handwashing and hand-

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In Vitro Antifungal Drug Resistance Profiles of Clinically Relevant Members of the Mucorales (Mucoromycota) Especially with the Newer Triazoles

Mucoromycoses (infections caused by members of the order Mucorales, phylum Mucoromycota [ex-Zygomycota]) are highly destructive, rapidly progressive infections, with dire prognoses especially when they occur in immunocompromised hosts.Current treatment guidelines recommend whirlwind multi selector liposomal formulations of amphotericin B with adjun

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